In September 2023, the U. 253 reviews submitted with a 8. paigeintx • 21. You should consult your health care professional before taking any drug, changing your diet, or commencing or discontinuing any course of treatment. ago Customer service is excellent. Tirzepatide is a novel drug that has shown promising potential for both diabetes management and weight loss. I assume this is because the subject is adjusted to the peptide. Additionally, tirzepatide was associated with a meaningful reduction in HbA1c, with normalization to nondiabetic levels in nearly half of the tirzepatide groups. With millions of active users and page views per month, Reddit is one of the more popular websites for discussions online. Food and Drug Administration updated the label for Ozempic to include that ileus, or blockage of the bowel, has been reported as a possible adverse reaction. And injecting into the thigh slows absorption rate for most people which helps decrease the side effects. There are many discussions in this sub on the topic, but basically, the half life of the drug is only 117 hours. Let the alcohol from your prep pad fully dry before injecting. (Tirzepatide is a diabetes drug made by Eli Lilly that also has weight loss effects. 5 every three days. This product is available in the following dosage forms:. The magic window is 72 hours after your first injection. I didn't feel all the crazy effects on that dose and felt fine. Whether you liked the compound or not and whether you'd use it again. The most common adverse events with tirzepatide were gastrointestinal, and most were mild to moderate in severity, occurring primarily during dose escalation. 5cc needle. 0mg for DM2, and 2. Not planning to go up anytime soon. Photo Credit: Shutterstock. Eat lots of protein, minimize carbs. I had a terrible experience with SAF. 25 and two months at 0. It is a peptide that comes from the stomach. First 2 weeks no appetite suppression and still just as hungry. All strengths of tirzepatide are currently listed as available, but a company spokesperson said that could vary by location and demand. 5 cc/mL) is NOT a lot to inject. Tirzepatide injection site. Tirzepatide is administered through subcutaneous injection (under the skin). Jun 4, 2022 · The most common adverse events with tirzepatide were gastrointestinal, and most were mild to moderate in severity, occurring primarily during dose escalation. Tirzepatide is an acylated peptide engineered to activate the GIP and GLP-1 receptors, key mediators of insulin secretion that are also expressed in regions of the brain that regulate food intake. It was removed from the market less than two years later after many women who used it had died or experienced life threatening side effects. Today I woke up with a full blown head cold, runny nose, sore throat and groggy feeling. It is a fusion protein that combines the properties of a glucagon-like peptide-1 (GLP-1) receptor agonist and a glucagon receptor antagonist. It definitely has helped curb my appetite. The lower doses are for "loading" and to allow adapting to the side-effects. So even though you're injecting the same dose, each week you're actually seeing a higher peak until you're on a stable dose. It varies from person to person. More patientstaking tirzepatide achieved target HbA1c of <7. Product is not. redwoman72 • 10mg-46F, 5'4-HW:270, MJ-SW:182, CW:145 (-37 lbs w/Mounj), GW:140 • 9 mo. Gonkulator5000 • 7 hr. 7%, and tirzepatide led to dose-dependent weight reductions between 7and 9. A more. Controlling high blood sugar h. Weekly shots give you a yoyo effect. 5 dose of tirzepatide three days ago. With the name brand it "kicks in" by the following day and hasn't worn completely off by the time the next injection day is. I started on compounded tirzepatide from a local weight loss clinic in May, then moved to a US-sourced peptide company in July (When the bulk rates were still offered. In an odd inversion of the previous SUSTAIN 7 trial (where semaglutide showed superiority to dulaglutide), Tirzepatide was trialed against the current 1. Other side effects of Tirzepatide. Rotate injection sites with. If you're calendar-challenged, there are. I did the compounded tirz from ACA pharmacy. Adverse events caused treatment discontinuation in 4. So maybe they also underdose or use inferior products. Eli Lilly's drug, tirzepatide, if approved, could cost more than $1,500 a month if the price turns out to be like that of a similar drug made by Novo Nordisk. I am currently taking tirzepatide once weekly and aod 9604 5 days on and 2 days off. COMMON BRANDS Mounjaro DRUG CLASS GIP and GLP-1 agonist CONTROLLED SUBSTANCE CLASSIFICATION Not a controlled medication GENERIC STATUS No lower-cost generic available AVAILABILITY Prescription only Reviewed by: Kristianne Hannemann, PharmD. ago I was. The lack of side effects doesn’t mean that the shot isn’t working. In the semaglutide study, 50% of folks on the placebo experienced GI side effects. 25 sema. 50 units (0. 1% for placebo. 5 mg dose. Adrenochrome is not an approved pharmaceutical drug and has not been extensively studied for its potential side effects. If you add 5mL of bacteriostatic water to the vial, you've made 5mg/5mL, or a concentration of 1mg/1mL. Use with caution in patients prone to dehydration. So- I switched to semiglutide peptide compound. After 4 weeks: The dosage should be increased to 5 mg subcutaneously once a week. [deleted] • 5 mo. 625 worked fine with almost no side effects, but the appetite came back on day 3 or so. My 4/11 order of Peptide Sciences has consistently, across all 3 vials caused me a raised 1 inch long, 3/4 inch wide super itchy rash that lasted nearly the full week. It's only been a week, I would stay at the present dose for a couple weeks and let it build up some. Tirzepatide face. 5mg dose. I would stop the zofran. 5mg no side effects on week 4 with 8 lbs lost. Gabbay notes that studies on the potential cardiovascular benefits are ongoing. Gonkulator5000 • 7 hr. The stress on the body from rapid weight loss and malnutrition (low protein and low zinc, iron, fatty acids to name a prominent few) are likely the cause of the hair loss. Side effects were some nausea and constipation, which has stopped happening now. Some back story, I have PCOS and I did my first month of 2. Tirzepatide is a weekly injection that can help lower blood sugar for people with Type 2 diabetes. I think I got more nausea AND more good effects from injecting near the belly button. I can tell you from experience the difference between tianeptine sodium (Rx pill) and sulphate (Chinese research chemical) was night and day--one was short-acting with no side-effects & the other lasted longer but burned the shit out of my stomach lining, and there's no telling what long-term effects it had. ago I just started with https://drsemorednp. It may be my total imagination, but I have had some effects. Product is fine, no complaints there, but not better and they take longer and cost more than ACA. Most experience at least mild side effects. “It’s working like it should,” she said. Eberwein has confirmed to me that fewer side effects are consistently seen with Tirzepatide in comparison to Semaglutide, and that's in addition to the lower discontinuation rate. So maybe they also underdose or use inferior products. I am now 249 lbs. I do not currently have any 'injury' or acute inflammation, other than perhaps the general inflammation related to. • 6 mo. 281 -> 211 at 6'7". Gonkulator5000 • 7 hr. Tirzepatide is a potent medical compound that mimics two types of hormones. The effects wane at lower dosages, that's one of the reasons there are 6 dosing steps. Both drugs are manufactured by Novo Nordisk. See if your pharmacist says the same. 4lbs total loss) mild nausea occasionally, sometimes felt like it was due to hunger. Side pocket of the dress and drilled again go in what kind of weird hobby is this suddenly su yi flashed could it be that she wanted to hide here how often cryotherapy for weight loss Shark Tank Keto Pills Review and go out after this thought appeared in his mind su yi. doi: 10. The new weight loss drug, tirzepatide. For additional glycemic control: Increase dosage in 2. Although tirzepatide demonstrated its superiority in reducing weight at doses of 5 mg, 10 mg, and 15 mg compared to semaglutide at 1 mg in SURPASS-2, 16 a comparison of tirzepatide with semaglutide at a dose of 2. It’s also an incredibly powerful platfor. I have very little appetite and work out 2/3x per week. Gaining weight on 5MG. Allowing a conservative estimate, if ≈10% of patients discontinued tirzepatide on the basis of side effects, only ≈2. The effects wane at lower dosages, that's one of the reasons there are 6 dosing steps. 125mg weekly, but with much more stable amounts in my system at any given time. However, in clinical trials, Tirzepatide demonstrated superior weight loss results compared to other GLP-1 receptor agonists, catching the attention of the weight loss community. Only difference is no B6. Sulfur burps appear to be a somewhat rare side effect of semaglutide, tirzepatide, and other drugs in their class, known as GLP-1 receptor agonists. I’ve been doing pretty well on 2. Go to Tirzepatide r/Tirzepatide • by Lange268. Roughly one in 10 Americans have diabetes, and 90-95% of those have type 2 diabetes ( 1 ). This product is available in the following dosage forms:. Check with your doctor immediately if any of the following side effects occur while taking tirzepatide: More common. View community ranking In the Top 5% of largest communities on Reddit. 5mg for meI am sticking with it!. If you're worried about hypoglycemia (low blood sugar levels), rest assured that tirzepatide poses a relatively small. com/ and her prices are pretty low. I lost 30 lbs on the compounded semaglutide and my A1C dropped to 5. Get your doctor to switch you to Wegovy if your insurance will cover it. SW 319 and CW is 310. In August 2023, I started doing peptide tirzepitide with no effects whatsoever. First three months were great, saw great improvement in symptoms (specifically inflammation). If the shots are hard to find then sublingual B12 tablets work well too. A few ways to prevent/minimize include: Hit a protein goal of 0. Compounded/reconstituted / brand name. 5 per three days, for a total of 6. He loves Mounjaro and he is fine with what I'm doing, he just cautioned me to be careful that I'm getting a good product. If you will be using tirzepatide at home, your doctor will teach you how the injections will be given. The only thing that did come back that I hadn't really noticed was gone was tinnitus. It comes in 2,5,10mg ( well I bought the 2mg a while ago). But from my research on other forums, people are saying that liraglutide > semaglutide > tirzepatide. I switched to tirzepatide from ACA a month ago. Semaglutide has an average rating of 6. Talk to your doctor if your symptoms of fatigue continue or are severe. 5 per week, and because the drug has a 117 hour half life, I started with 2. It definitely has helped curb my appetite. “It’s working like it should,” she said. I am looking for a pharmacy that delivers to NY state and compounds tirzepatide (mounjaro) with something besides B vitamins, which give me cystic acne at high doses. Down 39 lbs. Thus, it requires a relatively lower dosage to achieve its results. Tirzepatide has also been shown in clinical trials to be useful for weight loss, although currently it is not an FDA-approved weight loss drug. Most of these are transient and go away over the first several weeks. 9 comments. So to answer your question, for me it was right away and already felt better after my second shot. 5mg on Day 7. you can buy the same product from China at a much lower cost (1/5th the cost). 1 / 2. It worked immediately, but the side effects didn't seem to subside (nausea). Both drugs are manufactured by Novo Nordisk. Perhaps one of the most significant (and only clinically significant) differences between that of a GLP-1 agonist and tirzepatide concerns absorption of concurrent oral medications. Tirzepatide from Core Peptides. 4lbs total loss) mild nausea occasionally, sometimes felt like it was due to hunger. Tirzepatide is a type of medication known as an incretin mimetic. They do not work when frozen. I'm taking 6mg per week. MeMostyPosty • 3 days ago It’s so ugh, but worth it javadwc • 3 days ago As a few others have said Tirz will probably cost you 3 times as much. The pen has a needle and a dial to turn for each dose. Right now I'm taking 5mg/week, so it's $200/month. Take something for nausea and pay attention to foods your. Compounded tirzepatide specifically refers to the customized formulation of this medication by a compounding pharmacy. Along with its needed effects, tirzepatide (the active ingredient contained in Mounjaro) may cause some unwanted effects. you can buy the same product from China at a much lower cost (1/5th the cost). Tirzepatide is stronger but it’s recommended to start with 2. Eli Lilly's obesity drug tirzepatide has shown promising weight loss results in a pivotal Phase III trial. kidney problems --little or no urination, swelling in your feet or ankles, feeling tired or short of breath. If you can't understand the label ACA has a customer service line that can help you and if they can't help you then you should be calling you're doctor. 50 units (0. you can buy the same product from China at a much lower cost (1/5th the cost). Updated Half Life Plotter. Currently, the FDA lists the following as potential side effects of tirzepatide: nausea. Then you reconstitute it and give yourself the injections. Then you reconstitute it and give yourself the injections. The most common side effects from tirzepatide were gastrointestinal, such as nausea, diarrhea and constipation, which were generally mild to moderate in severity. Definitely thankful for no side effects. 625 worked fine with almost no side effects, but the appetite came back on day 3 or so. ago Oh there's a powder version hmm i don't mind the compound injections they seem to be working with no side effects Qweylow • 1 mo. Last updated on Dec 24, 2022. The first injection of semaglutide took days to notice any difference in the way I felt. I've been on Tirzepatide 2. In Eli Lilly's SURMOUNT-1 clinical trial, its experimental obesity drug—a weekly injection called tirzepatide—helped clinical trial patients lose roughly one-fifth of their body weight. Tirzepatide experience. I have eaten very small amounts of bland food. It is currently sold under the brand name Mounjaro™ or Zepbound. walking 20-30 min may be the extra calorie burn you need to bump you up. I'm on compounded tirzepatide/B6 and I give myself a separate B12 shot every week. 0% for 10 mg and 66. 4 mg once weekly significantly reduces body weight by approximately 15%, with simultaneous improvement in cardiometabolic risk . My understanding is that the side effects are the same as Ozempic but possibly more intense. I'm hoping my vision clears up once the med is out of my body. I had zero side effects but also zero weight loss. Icy-Bowl-8103 • 23 days ago. The most common side effects associated with tirzepatide are related to gastrointestinal tract like nausea, vomiting and diarrhea [20,21]. Curious your experience : r/Tirzepatide. My provider is offering Tirzepatide compounded with BPC-157. If there is 2ml of liquid in the vial, then the weekly dose of 2. I microdosed to avoid side effect as i was concerned of nausea and fatigue which would interrupt me going to the gym because while im losing weight i did not want to lose muscles. ago Yes they do work. Been dosing 2. In addition to it's effects on blood sugar and. You can get this shipped very fast. Why is this happening?? Anyone? 1 Firegrlnikki • 3 days ago I ship from Hallandale Pharmacy 1 Missyresister • 3 days ago Can I skip one week?. I'm on 5 mg now and since dosing I feel like this is so much more powerful than what i was getting thru the pharmacy. I started at 5 mg. I just informed my PCP this morning that I've been taking Tirzepatide. Tirzepatide is administered through subcutaneous injection (under the skin). 15mg is $425. A full. Tom Sanders, professor emeritus of nutrition and dietetics at King's College London said higher doses of tirzepatide led to more weight loss, but they caused more side effects, mainly nausea. Thinking about switching. Tirzepatide is a new molecule capable of controlling glucose blood levels by combining the dual agonism of Glucose-Dependent Insulinotropic Polypeptide (GIP) and Glucagon-Like Peptide-1 (GLP-1) receptors. I ordered peptides (ap) to try to tide myself over for the month. The adverse drug reaction profile of tirzepatide is comparable to GLP-1 agonists, as it is a dual GIP/GLP-1 agonist. It is currently sold under the brand name Mounjaro™ or Zepbound. It varies from person to person. OOOPS, I agree! I forgot to add the formula! This is what the label says "Tirz 12. What side effects can this medication cause? What should I know about storage and disposal of this medication? In case of emergency/overdose What other information should I know? Brand names IMPORTANT WARNING: Tirzepatide may cause thyroid C-cell tumors. I've been on trizepatide compound for 2 months with little side effects. 5cc to 2500mcg or 2. 5'3 165lb down to 130 with SG in about 6m. The most common side effects associated with tirzepatide are related to gastrointestinal tract like nausea, vomiting and diarrhea [20,21]. You can get these quickly (3-5 days). You will need to make your own copy and. The side effects include nausea. I did one month at 0. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. 5mg Tirz every other day,. Not sure if she's available in AL and if it's cheaper than $525 a month. Continue reading. However, if you want tirzepatide for weight loss, you may have a battle on your hands. 3 mls before I felt the heart rate go up. I went up to 1. They are putting me on Tirz at 2. 5'3 165lb down to 130 with SG in about 6m. Tirzapatide is a glucagon-like peptide-1 (GLP-1) receptor agonist. I just finished 3 months on sema, last month's dose was 1. I'm looking to stack for several reasons: Tirz is more expensive, to get the existing stock of Tirz to last longer, and I'm a believer that multiple molecules can have a synergistic effect. It has been a great experience so far. Average weight reductions ranged from 16% at the low, 5-mg dose, to 22. 5mg for meI am sticking with it!. First 2 weeks no appetite suppression and still just as hungry. Lack of side effects. It is the first of its kind to act as a dual-acting glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptor agonist [2,3]. GIP and GLP1 are incretin hormones: they are released in the intestine in response to nutrient intake and stimulate pancreatic beta cell. The dropout rates were 15. Medical experts have deemed the injectable drug . Three weeks ago- I tried retatrutide. "While they're the same drug, they're under different brand names and have a slightly different dosing schedule," she said. The most frequently reported GI side effects were nausea and diarrhea, which affected anywhere between 10-25% of the participants, depending on tirzepatide dose. 3mg Friday, 3mg Tuesday. sites like bitplay
Other new GLP-1 and GIP receptor agonist. . Tirzepatide compound reddit side effects
These side effects may go away. 5mg every 5 days which is about 6 doses=45mg then it's kinda yeh same except your taking less dose more frequently. Gonkulator5000 • 7 hr. Lost 30lbs. I actually started on saxenda, which is Liraglutide and I did very. The animals treated with the drug also appeared to burn more energy than the mice on placebo, despite being on the same calorie restriction. You may report side effects to the FDA at 1-800-332-1088. 625 as my 3rd injection (after I got undesirable side effects after the 1st injection of 2. Went away after a few hours. The cost for Emerge is $410 for the month. The percentage of patients with a weight loss of 5% or more was 85% to 91% based on dose, compared to 35% with placebo. how sick do you normally get on a dose? I would think it might just be a little bit MORE side effects than usual, but very likely to be totally manageable!. For whatever reason I'm nervous that it won't work as well since I'm restarting and am considering just jumping to 5mg. 5 comments Add a Comment Tim3k- • 3 hr. Lilly, the manufacturer of Mounjaro, reported that tirzepatide can help people with type 2 diabetes to lose almost 16% of their body weight. 5, 3. I'm in the process of doing this. MeMostyPosty • 3 days ago It’s so ugh, but worth it javadwc • 3 days ago As a few others have said Tirz will probably cost you 3 times as much. 5 but this new 5mg is working wonders! It's interesting, I'm guessing it. Mounjaro (tirzepatide) for Diabetes, Type 2 "I completed 4 weeks on 2. All drugs may cause side effects. Encourage fatty acid synthesis from glucose. I have insulin resistance PCOS and really struggle losing weight. Call your doctor rightaway if you have a neck mass, trouble breathing, trouble swallowing,or have hoarseness that will not go away. You would want to get your body use to the new medication and minimize side effects. Manufactured semaglutide and tirzepatide come in pen form with preset dosing amounts. But the FDA has raised concerns about salt-compounded forms of semaglutide, which. Are there any side effects that you've observed, anything you would do differently to perhaps mitigate these side effects if any. This means that Tirzepatide may have a broader range of effects on appetite and metabolism. After years of trying everything, I am finally feeling hopeful. I mixed up my Nad+ shot with my wife's Tirzepatide - BPC 157 shot, 45 units. A new. I DO get an injection site reaction, but apparently so does like 50% of people on tirz. After 4 weeks: The dosage should be increased to 5 mg subcutaneously once a week. Tirzepatide comes as a solution (liquid) in a pre-filled pen to be injected subcutaneously (under the skin). It caused constipation while tirzepatide seems to be causing the opposite problem so far. 5 mg or 10 mg. My provider is offering Tirzepatide compounded with BPC-157. 9% for the 15 mg dose. ago Customer service is excellent. 5 dulaglutide, but now dulaglutide. Max dose is 15 mg/ week. These are not. OOOPS, I agree! I forgot to add the formula! This is what the label says "Tirz 12. 5 mg. In some cases, they increase, temporarily, with. I'm now 5 weeks in to using Tirzepatide. The effect of tirzepatide treatment on cardiovascular events has been studied in SURPASS-4, a trial involving patients with known coronary, peripheral arterial, or cerebrovascular diseases or those who were at a high risk of these diseases. They do not work when frozen. Both have been listed on the FDA's drug shortage site for months. I also have extreme fatigue on both semaglutide and tirzepatide. In some cases, they increase, temporarily, with. 3 comments. Adrenochrome is not an approved pharmaceutical drug and has not been extensively studied for its potential side effects. The drug, called tirzepatide, works on two naturally occurring hormones that help. a 1:1:1:1 ratio, to receive tirzepatide at a dose of 5 mg, 10 mg, or 15 mg or semaglu - tide at a dose of 1 mg. It took my body some time to adjust to the medicine and for the weight to start coming off. I am now stacking the two. Based on animal reproduction studies, there may be risks to the fetus from exposure to tirzepatide. Then last week I started having diarrhea and I'm now on day 7 of that. I don't have any other health issues besides high blood pressure. But if I end up going to higher and higher doses, it won't be long before $500/month comes close or is a better price than online. I just signed up. Chinese made compound materials are common in this type of operation. In separate trials, tirzepatide has resulted in greater weight loss than. I'm not sure what that means long-term but found it interesting. These are not. Controlling high blood sugar h. Stacking Both Ways. Also, there is a common misconception on this sub about what a peptide is, so this is to help with clarity and not an attack on your post. With the second dose came nausea, severe diarrhea, and stomach (area) pain. I think they're $250. then went up to 5 mg and felt terrible so I tried 4 mg but still felt a little off. They haven't tested a lot of things, that doesn't make them unsafe. Different side effects from new pharmacy. Sarahbee222 • 7 mo. 5-2#s by Saturday and then I slowly start to pick it back up until I start all over again on Thursday. Routine monitoring of serum calcitonin or using thyroid ultrasound is of uncertain value for early detection of MTC in patients treated with tirzepatide 1. I'm not sure when it's supposed to be working but I do notice I'm still having food noise and still have to eat every 3-4 hours. I am looking for a pharmacy that delivers to NY state and compounds tirzepatide (mounjaro) with something besides B vitamins, which give me cystic acne at high doses. 4mg was recently approved for chronic weight management (SUSTAIN 7 was 1. mg dosage, so it lasts 4 shots/weeks. I got reasonably good results from loperamide/simethicone (immodium/gasx) as well but it would leave me constipated for too long. It's an attractive business model, I'm sure making killer profit. But the most annoying effect was in fact that faint-like feeling when I suddenly got up after lying down. Read this article that Tirzepatide was actually more effective than Semaglutide so I decided to give it a go. Eli Lilly's drug, tirzepatide, if approved, could cost more than $1,500 a month if the price turns out to be like that of a similar drug made by Novo Nordisk. Tirzepatide, sold under the brand name Mounjaro, is an antidiabetic medication used for the treatment of type 2 diabetes. I just bought some tirzepatide from Peptide Sciences. In this. For additional glycemic control: Increase dosage in 2. ago Yes they do work. The percentage of patients with a weight loss of 5% or more was 85% to 91% based on dose, compared to 35% with placebo. On the other hand, the weight loss effect of 15 mg Mounjaro is double that of Ozempic 1 mg. I actually started on saxenda, which is Liraglutide and I did very. 5 over 3 shots) and am coming up on my 2nd week. Mounjaro (generic name: tirzepatide) does not cause fatigue, which can leave you feeling tired, weak and with low energy. Apr 27, 2023 · Tirzepatide and semaglutide have similar side effects. I have been getting compounded Tirzepatide from ACA through push health, which is compounded with a B vitamin to help with nausea. 5mg you will do following for a. hotnewbombshell • 1 min. Mounjaro (tirzepatide), from Eli Lilly, is a dual-acting GIP (glucose-dependent. AdorableTrainer1486 • 1 mo. I can't find any sterile compounding pharmacies in Alabama. I've only been on it for 4 weeks now but I know some people have been using it for 2 or 3. I am an idiot. Hi Supaa69, could you also dm me the info. But with the compound it literally took 3 days before I could feel the effects, and the night before. She liked TZ better and had less bad symptoms and more food noise suppression so I. 0 million adults could tolerate maximum doses. Mounjaro Tirzepatide injection is used to treat type 2 diabetes. 5mg of tirz/b12 in May. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Max dosage of semaglutide is 2. I am watching what I eat and sticking to a calorie deficit and walking 2 miles 3-4 times a week. Although tirzepatide demonstrated its superiority in reducing weight at doses of 5 mg, 10 mg, and 15 mg compared to semaglutide at 1 mg in SURPASS-2, 16 a comparison of tirzepatide with semaglutide at a dose of 2. But your likelihood of side effects is also low. We start everyone off at a low dose and increase as you tolerate the medicine. Semaglutide is the active compound that Ozempic and Wegovy are made of, while Mounjaro contains a compound called tirzepatide. I've tried two different vials and it just doesn't seem to have any effect with the. It is the first of its kind to act as a dual-acting glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptor agonist [2,3]. Looks like I'll have to try and get the name brand stuff. HelloFox • 2 mo. Just finished my second week of 2. Controlling high blood sugar helps prevent kidney. 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